The Science of Reading, rooted in research and evidence-based practices, has emerged as a powerful approach to reading instruction that holds the promise of transforming communities and nations through the power of literacy. This book delves into the fundamental principles and research findings behind the Science of Reading, highlighting its potential benefits for individuals, communities, and nations. Additionally, it explores the challenges and barriers in implementing this approach and offers strategies for successful adoption. Furthermore, it examines the crucial roles of educators and policymakers in promoting and supporting Science-based Reading Instruction. By embracing this transformative approach, societies can unlock the full potential of literacy and pave the way for a brighter future.